Raul Eduardo Rivera Quiroga
Antonio Narino University, Colombia
Title: First multicenter characterization of oral yeasts from healthy individuals in Colombian dental clinics
Biography
Biography: Raul Eduardo Rivera Quiroga
Abstract
Few studies in Colombia provide an approximation of the prevalence of oral fungal colonization, data related to diff erent species
or their biological, clinical and epidemiological aspects. Considering this, a multicenter study was carried out to identify the
most frequently occurring oral yeasts in healthy adult individuals who attended dental clinics at the Antonio Nariño University
in nine diff erent Colombian cities. Oral rinse samples were obtained from 96 adult healthy patients and cultured and identifi ed by
panfungal PCR sequencing. Association between sociodemographic variables and oral health habits with presence of oral fungi and
mixed colonization was made by a correspondence analysis and contingency table and logistic regression was performed to evaluate a
possible relationship between these variables with a signifi cance of p<0.05. 57.3% of healthy individuals had oral yeast and 21.8% had
mixed colonization. Th e most prevalent yeast was Candida albicans (52%), C. parapsilosis (17.9%) and C. dubliniensis (7.57%). Yeasts
with low frequency (1.5%), included Pichia kluyveri, Rhodotorula mucilaginosa and Geotrichum candidum. Yeasts most frequently
associated in mixed colonization were Candida albicans and Candida parapsilosis. Th e presence of mixed colonization was related
to the use of dental prostheses (P<0.006), dental aparatology (P<0.016) and O´leary index (P<0,012). Th is is the fi rst study that
characterizes oral yeast in a Colombian healthy population, showing a relationship between using dental prostheses and having dental
appliances with having mixed colonies of oral yeasts and reveals a possible synergy between C. albicans and C. parapsilosis.