Erfan Abbasi Atibeh
Hamedan University of Medical Sciences, Iran
Title: Leukocyte-platelet rich fibrin and enamel matrix derivative use as additive material in guided tissue regeneration technique: A randomized clinical trial
Biography
Biography: Erfan Abbasi Atibeh
Abstract
Background: GTR technique is the gold standard for periodontal intrabony regenerative therapy. The aim of this study was
to evaluate the effect of using L-PRF and EMD growth factors along with GTR technique for regeneration of periodontal
intrabony defects.
Methods & Materials: Forty-five intrabony defects resulted from periodontal disease which can be reconstructed were enrolled in the study. Group 1 just got GTR treatment as control group, group 2 got L-PRF along with GTR treatment and in group three EMD used along with GTR. Clinical factors such as periodontal probing depth (PPD), clinical attachment level (CAL), keratinized gingival width (KGW) and bleeding on probing (BOP) were evaluated before and six months after treatment. Also amount of bone fill was evaluated with standard radiography.
Result: Treatment in all three groups significantly result in reduction of PPD and gaining of CAL. Sites with BOP significantly decreased, defects significantly filled with bone, however, there was no significant difference in KGW. Intragroup comparison showed no significant difference among groups in evaluated factors. But the most PPD reduction was 5.4±1 in L-PRF+GTR
group, the most CAL gain was 3.37±2 in GTR group, the most reduction in BOP sites were 14 sites in L-PRF+GTR groups and the most bone fill was 73% in GTR group.
Conclusion: Using EMD or L-PRF along GTR treatment does not have additional effect on positive results of GTR treatment alone.